Table 3 Genes involved in the Biological Process of the up-regulated genes
Biological Process | Gene No. | Gene Name |
|---|---|---|
Transcription | 22 | PWP1, ZNF202, SIN3A, CRSP3, SUD33, CDK7, BCOR, RNF2, ZNF77, SND1, SOX30, PHD finger protein 3, NOTCH4, CBX3, MNAT1, MAF, RXRA, TEAD3, SMAD6, MYC Binding protein 2 and SP11O |
Regulation of transcription, DNA-dependent | 17 | SMAD6, CBX3, RNF2, SND1, ARNT, SPEN, TEAD3, PHF3, LOC643641, MYCBP2, SP110, SUDS3, ZNF77, ZNF202, RXRA, MAF |
Biological process unknown | 9 | FETUB, UBQLN4, SURF5, PRCC, HSD17B1, ZNF77, BTBD1, SIPAILI, RXR4 |
Proteolysis | 8 | TMPRSS4, ADAMTS7, MMP23B, AZU1, PGM5P1, SPPL2B, ICEBERFG (caspase-1 inhibitor), GZMK |
Protein amino acid phosphorylation | 7 | MAP4K4, CDK7, DYRK2, SYK, FGFR1, MARK4, RIPK2 (down regulate TLR 2/3/4, IL1 and IL8 receptor |
Transcription from RNA polymerase II Promotor | 6 | TCEA1, TEAD3, MNAT1, SOX30, CRSP3 |
Intracellular signaling cascade | 6 | SH2B3, MCF2L, SYK, Rho GTPase activating protein, CAPS, CHN1 |
Ubiquity cycle | 6 | OTUB2, MYCBP2, CBLB, FBO31, CDC23, VPS8 |
Signal transduction | 6 | ARNT, RXRA, GAS6, TNFSF13B, ADORA1, RIPK2 |
Cell proliferation | 6 | CDK7, MNAT1, SYK, CSE1L, GAS6, TNFSF13B |
Metabolism | 5 | QDPR, ATP2C1, HSD17B1, GSTM4, ECHS1 |