From: Streptococcus pneumoniaeearly response genes to human lung epithelial cells
Function/gene name | Protein | TIGR4 genome acc. No. | A549a | THP-1b | ||
---|---|---|---|---|---|---|
 |  |  | 0.5 h | 1 h | 0.5 h | 1 h |
Cell envelope | ||||||
cbpI c | choline binding protein I | SP0069 | Â | 2.8 | Â | 8.4 |
bgaA | beta-galactosidase | SP0648 | Â | 17.0 | 3.4 | 26.9 |
nanA c | neuraminidase A, authentic frameshift | SP1693 | Â | 16.5 | 3.9 | 47.1 |
Energy metabolism | ||||||
agaS | sugar isomerase domain protein AgaS | SP0065 | Â | 5.6 | Â | 10.3 |
glgA | glycogen synthase | SP1124 | Â | 3.8 | Â | 5.4 |
 | acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase, putative | SP1162 |  | 2.7 | 4.9 | 6.0 |
scrB | sucrose-6-phosphate hydrolase | SP1724 | 3.0 | 4.4 | 2.4 | 4.7 |
galT | galactose-1-phosphate uridylyltransferase | SP1852 | Â | 2.7 | 2.6 | 4.4 |
galK | galactokinase | SP1853 | Â | 2.3 | 2.3 | 2.8 |
recP | transketolase | SP2030 | Â | -3.6 | -2.0 | -2.5 |
gplK | glycerol kinase | SP2186 | Â | 3.0 | Â | 4.1 |
Hypothetical proteins | Â | Â | Â | Â | Â | Â |
 | hypothetical protein | SP0052 | -3.5 | -5.6 | -2.6 | -3.5 |
 | hypothetical protein | SP0067 | 2.4 | 2.1 |  | 4.1 |
 | conserved hypothetical protein | SP0159 | -2.3 |  | -2.0 |  |
 | conserved hypothetical protein | SP0742 |  | -2.9 | -6.5 | -3.2 |
 | conserved hypothetical protein | SP1003 |  | 2.1 | 2.1 | 3.4 |
 | hypothetical protein | SP1059 |  | 4.4 | 56.3 | 16.0 |
 | conserved hypothetical protein | SP1174 |  | 2.4 | 2.7 | 4.4 |
 | hypothetical protein | SP1198 | 2.7 | 2.6 |  | 2.8 |
 | hypothetical protein | SP1199 | 2.9 | 2.0 |  | 2.2 |
 | hypothetical protein | SP1677 |  | 10.3 |  | 14.6 |
 | hypothetical protein | SP1678 | 2.9 | 6.1 |  | 6.9 |
 | hypothetical protein | SP1679 | 4.6 | 9.6 |  | 6.6 |
 | conserved hypothetical protein | SP1680 | 5.3 | 11.5 | 2.0 | 14.6 |
Others | ||||||
 | lactose phosphotransferase system repressor, degenerate | SP0169 |  | 2.2 | 15.4 | 6.0 |
acpP | acyl carrier protein | SP0418 | -2.0 | Â | -2.3 | Â |
fabF | 3-oxoacyl-(acyl-carrier-protein) synthase II | SP0422 | -2.4 | Â | Â | -5.1 |
bta | bacterocin transport accessory protein | SP1499 | -2.7 | -2.4 | -4.2 | -2.2 |
Protein synthesis | ||||||
rpsD | ribosomal protein S4 | SP0085 | Â | 2.7 | Â | 2.4 |
rpsJ | ribosomal protein S10 | SP0208 | Â | 4.1 | Â | 2.9 |
rpsC | ribosomal protein S3 | SP0215 | Â | 2.0 | 2.2 | Â |
infC | translation initiation factor IF-3 | SP0959 | Â | 2.5 | 2.2 | 2.3 |
rpmI | ribosomal protein L35 | SP0960 | Â | 3.9 | 2.2 | Â |
rpsF | ribosomal protein S6 | SP1541 | 2.9 | 3.0 | Â | 2.2 |
yfiA | ribosomal subunit interface protein | SP2206 | Â | -3.9 | -2.6 | -2.5 |
Purine and pyrimidine ribonucleotide biosynthesis | ||||||
purC c | phosphoribosylaminoimidazole-succinocarboxamide synthase | SP0044 | -5.1 | -4.7 | -2.4 | -7.8 |
purH | phosphoribosylaminoimidazolecarboxamide formyltransferase-IMP cyclohydrolase | SP0050 | -15.3 | -4.1 | -4.3 | -5.5 |
purE c | phosphoribosylaminoimidazole carboxylase, catalytic subunit | SP0053 | -6.4 | -8.5 | Â | -4.2 |
carB | carbamoyl-phosphate synthase, large subunit | SP1275 | Â | -4.2 | Â | -2.6 |
pyrR | pyrimidine operon regulatory protein | SP1278 | -2.1 | -7.8 | -2.3 | -4.4 |
Transport | ||||||
 | PTS system, IIA component | SP0064 | 2.2 | 3.4 |  | 6.5 |
 | PTS system, mannose-specific IID component | SP0282 | -3.7 |  | -2.4 |  |
 | xanthine-uracil permease family protein | SP0287 | -8.4 | -5.3 |  | -2.3 |
 | PTS system, IIC component, putative | SP0647 |  | 4.3 | 3.5 | 8.2 |
 | ABC transporter, permease protein | SP1688 |  | 5.3 | 2.4 | 13.6 |
 | ABC transporter, permease protein | SP1689 |  | 2.8 | 3.7 | 18.9 |
 | ABC transporter, substrate-binding protein | SP1690 |  | 2.1 | 3.9 | 21.6 |
msmE | sugar ABC transporter, sugar-binding protein | SP1897 | Â | 2.1 | Â | 4.1 |
malD | maltodextrin ABC transporter, permease protein | SP2110 | Â | 2.6 | 2.1 | 6.4 |
Unknown function | ||||||
 | vanZ protein, putative | SP0049 | -2.9 |  | -3.4 | -4.9 |
 | ACT domain protein | SP0238 | -2.1 | -3.4 |  | -2.3 |
 | HIT family protein | SP0521 |  | -2.4 |  | -2.1 |
 | flavoprotein | SP1231 |  | -2.0 | -2.3 |  |