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Table 1 Odds ratios of Alzheimer's disease, taking subjects with the BACE1 rs638405 C allele and without APOE4 as reference

From: The synergy factor: a statistic to measure interactions in complex diseases

BACE1

APOE4

Controls

Cases

OR

C+

-

125

80

Reference

GG

-

80

38

0.742

C+

+

48

74

2.409

GG

+

19

60

4.934

Totals

 

272

252

 
  1. Data from Nowotny et al 2001 [13].APOE4 = the ε4 allele of apolipoprotein E; BACE1 = the β-site APP-cleaving enzyme; C+ and GG refer to BACE1 exon 5 C/G (rs638405) genotypes; APOE4+ and BACE1 C+ pool homozygotes and heterozygotes of the respective alleles; OR = odds ratio
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BMC Research Notes

ISSN: 1756-0500

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