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Table 1 List of abbreviations

From: In silico investigation of ADAM12 effect on TGF-β receptors trafficking

abbreviation

definition

p R

Receptors production rate

k ie

Internalization rate towards endosome

K re

Recycling rate from endosome

k ic

Internalization rate towards caveosome

K rc

Recycling rate from caveosome

k cd

Constitutive degradation rate

k lid

Ligand induced degradation rate

k a

LRC formation rate

LRC

Ligand-receptor complex

R m

Receptor complexes in the cell membrane

R e

Receptor complexes in the endosome

R c

Receptor complexes in the caveosome

LRC m

LRCs at the cell surface membrane

LRC e

LRCs in the endosome

LRC C

LRCs in the caveosome

CIR

Constitutive to Induced degradation Ratio