Figure 2
From: In vivo activity of plant-based interleukin-12 in the lung of Balb/c mouse
Representative histological features of lung sections stained with hematoxylin-eosin after intratracheal administration of rIL-12, tIL-12 and non-transgenic wild type tomato extract. Lung sections 2 h after administration of non-transgenic wild type tomato extracts (A), 12 h after tIL-12 administration (B), where alveoli with fibrilar material mixed with activated macrophages (arrows) and lymphocytes are seen, and 24 h after rIL-12 administration (C, D). Some venules (V) and bronchioles (B) are surrounded by inflammatory cells (arrows).