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Table 1 Within-run and between-day precision of measurement of free β-hCG and PAPP-A, using Siemens Control Modules and human pooled sera on automated platform Immulite 1000

From: The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study

  

Free β-hCG (ng/ml)

 

PAPP-A (mIU/ml)

 

Sample

Control Module LFBCM

Human serum

Control Module LPCCM

Human serum

 

Control 1

Control 2

Control 3

 

Control 1

Control 2

 

Target

5.1

23.8

74.2

 

0.40

1.96

 

2SD Range

(4.2-6.4)

(19.8-27.8)

(63.6-90.8)

 

(0.32-0.48)

(1.70-2.22)

 

Within-run

       

Mean

4.84

24.1

72.8

66.6

0.41

1.94

2.58

SD

0.15

1.12

3.50

2.40

0.01

0.06

0.17

CV* (%)

3.09

4.65

4.81

3.60

2.44

3.09

6.59

Between-run

       

Mean

4.75

22.66

71.66

61.7

0.38

1.94

2.39

SD

0.31

1.70

5.25

4.13

0.02

0.11

0.21

CV* (%)

6.52

7.50

7.32

6.69

5.26

5.67

8.79

  1. CV* - coefficient of variation
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BMC Research Notes

ISSN: 1756-0500

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