From: Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr-1 in rat hippocampal slices
Conditions | c-Fos | Egr-1 | ||
---|---|---|---|---|
Fold change | P value | Fold change | P value | |
Propofol | 1.78 ± 0.17 | 0.09 ± 0.04 | ||
Propofol + RAS inhibitor | 0.51 ± 0.12 | 0.024 | 0.62 ± 0.09 | 0.046 |
Propofol + RAF inhibitor | 0.77 ± 0.08 | 0.041 | 0.67 ± 0.14 | 0.032 |
Propofol + MEK inhibitor | 0.74 ± 0.10 | 0.036 | 0.49 ± 0.09 | 0.029 |
Propofol + ERK inhibitor | 0.66 ± 0.11 | 0.032 | 0.59 ± 0.08 | 0.044 |
Propofol + MAPK inhibitor | 0.62 ± 0.13 | 0.021 | 0.55 ± 0.14 | 0.037 |