Table 2 Genotypic frequency distribution of MTHFR and statistically significant clinical variables in relation to MTHFR genotype
From: Analysis of the MTHFR C677T variant with migraine phenotypes
Clinical variables | Subtype (Total) | MTHFR Genotype % | ||
|---|---|---|---|---|
| Â | Â | CC | CT | TT |
Migraine Diagnosis | MO (102) | 39 (39%) | 61 (45%) | 2 (6%) |
P < 0.0001 | MA (165) | 61 (61%) | 74 (55%) | 30 (94%) |
Unilateral head pain | Y (123) | 40 (62%) | 63 (77%) | 20 (87%) |
P < 0.0001 | N (47) | 25 (38%) | 19 (23%) | 3 (13%) |
Physical activity | Y (149) | 51 (69%) | 78 (88%) | 20 (83%) |
P < 0.001 | N (38) | 23 (31%) | 11 (12%) | 4 (17%) |
Stress | Y (123) | 42 (61%) | 68 (76%) | 13 (52%) |
P = 0.002 | N (60) | 27 (39%) | 21 (24%) | 12 (48%) |