Table 1 Microarray platform characteristics
From: Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours
Platform | Technology | Sample labelling | Sample requirement | Number of features | Median probe spacing | Analysis |
|---|---|---|---|---|---|---|
Affymetrix Genome-Wide Human SNP Array 6.0 | Oligonucleotide (25 nt) | PCR reduction | 0.5 μg | 1,852 k | < 700 bp | DNA copy number and LOH |
Agilent Human Genome CGH 244A | Oligonucleotide (60 nt) | Whole genome | 0.5-1 μg | 236 k | 8,900 bp | DNA copy number |
Illumina HumanExon510s-duo | Oligonucleotide (25 nt) | PCR reduction | 0.75 μg | 511 k | 3,200 bp | DNA copy number and LOH |
Nimblegen HG18 CGH 385 k WG Tiling v1.0 | Oligonucleotide (50-75 nt) | Whole genome | 1 μg | 385 k | 6,270 bp | DNA copy number |