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Table 3 Detection of copy number of specific regions

From: Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours

Platform

0n: CDKN2A

TC-32

1n: 9p21.3-p21.2

TC-32

3n: Chr 8

TC-32

4n: 1q

TC-32

>10n: MDM2

OSA

 

Platform

Nexus

Platform

Nexus

Platform

Nexus

Platform

Nexus

Platform

Nexus

Affymetrix Genome-Wide Human SNP array 6.0

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Agilent Human Genome CGH 244A

Yes

Yes

Yes

0n

Yes

Yes

Yes

Yes

Yes

Yes

Illumina HumanExon510s-duo

Yes

Yes

Yes

Yes

Yes

Yes

3n/4n

3n

Yes

Yes

Nimblegen HG18 CGH 385 k WG Tiling v1.0 1

-

1n

-

Yes

-

Yes

-

3n

-

Yes

  1. 1Nimblegen's analysis software segments the data without scoring of copy number
  2. Detection of copy number of five specific chromosomes or chromosomal regions representing 0, 1, 3 and 4 copies in TC-32, as well as high-level amplification in OSA, using the platform-specific software and the platform-independent software Nexus.