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Table 4 Detection of copy number aberrations

From: Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours

Platform

TC-32

OSA

 

Homozygous copy loss

Loss

Gain

High copy gain

Homozygous copy loss

Loss

Gain

High copy gain

Affymetrix Genome-Wide Human SNP array 6.0

19

45

40

21

18

100

101

72

 

23

76

76

28

16

114

123

82

Agilent Human Genome CGH 244A

4

11

10

2

9

82

58

42

 

4

8

10

2

13

103

65

37

Illumina HumanExon510s-duo

3

32

21

3

2

75

77

33

 

3

33

19

2

4

86

78

36

Nimblegen HG18 CGH 385 k WG Tiling v1.0

0

7

15

2

1

31

62

36

 

0

11

6

0

1

25

55

36

  1. Number of copy number aberrations detected in chromosome 1-22 in TC-32 and OSA using the platform-independent software Nexus.