Figure 2From: Gene expression profiling of oxidative stress response of C. elegans aging defective AMPK mutants using massively parallel transcriptome sequencingComparison of gene expression level changes against oxidative stress between wild type and aak-2 mutants. (A) Correlation between gene expression level changes of all genes identified in stressed wild type and stressed aak-2 mutants relative to unstressed wild type. (B) Correlation between gene expression level changes of genes significantly up or down-regulated commonly in stressed wild type and stressed aak-2 mutants relative to unstressed wild type (green). The commonly up or down-regulated genes in stressed wild type and stressed aak-2 mutants show much higher correlation compared to all genes indicating these genes are not only commonly regulated in wild type and aak-2 mutants against oxidative stress, but also the degree of the expression level changes is overall quite similar. The commonly up or down-regulated genes in stressed wild type and stressed aak-2 mutants and their expression level changes in unstressed aak-2 mutants (orange). A large group of collagens are commonly up-regulated in stressed wild type and stressed aak-2 mutants, but insignificantly changed in unstressed aak-2 mutants as indicated.Back to article page