Table 2 Genotype and allele frequencies of the C1772T and the G1790A polymorphisms of the HIF1A gene in PE patients and the control group
Nucleotide | Amino acids | Genotypes | PE (%) | Control (%) | P-value | OR (95% CI) |
|---|---|---|---|---|---|---|
C1772T | Pro582 | CC | 137 (91.3) | 95 (90.5) | ||
Ser582 | CT | 13 (8.7) | 10 (9.5) | |||
TT | 0 (0.0) | 0 (0.0) | ||||
CT + TT | 13 (8.7) | 10 (9.5) | 0.203 * | 0.485 (0.178-1.067) | ||
Allele | ||||||
C | 287 (95.7) | 200 (95.2) | 0.831 | 0.906 (0.389-2.107) | ||
T | 13 (4.3) | 10 (4.8) | ||||
Genotypes | ||||||
G1790A | Ala588 | GG | 150 (100.0) | 104 (99.3) | ||
Thr588 | GA | 0 (0.0) | 1 (0.7) | |||
AA | 0 (0.0) | 0 (0.0) | ||||
GA + AA | 0 (0.0) | 1 (0.7) | 0.412 ** | 0.232 (0.009-5.737) | ||
Allele | ||||||
G | 300 (100.0) | 209 (99.5) | 0.411 | 0.232 (0.009-5.737) | ||
A | 0 (0.0) | 1 (0.5) |