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Table 3 Plasma miRNAs with significant change in expression after 1 year of 40.000 IU vitamin D 3 per week in the last five pilot subjects

From: Plasma profile of microRNA after supplementation with high doses of vitamin D3 for 12 months

miR

Fold change from baseline*

P value 12 month vs baseline**

let-7a

1.43

0.01

Let-7d

1.57

0.02

let-7f

1.59

0.02

miR-146a

1.46

0.04

miR-151-3p

1.28

0.02

miR-151-5p

1.39

0.01

miR-15b

1.37

0.04

miR-191

1.59

0.02

miR-221

1.63

0.01

miR-26a

1.96

0.02

miR-324-5p

0.59

0.03

miR-331-3p

1.45

0.02

miR-339-5p

1.60

0.03

miR-374b

1.43

0.03

miR-532-3p

0.47

0.01

miR-543

1.79

0.03

miR-766

2.08

0.01

miR-99b

1.82

0.01

  1. *A fold change >1 indicates up regulation after 12 months, whereas a value <1 indicates down-regulation after 12 months; **Paired t-test.