Table 2 Predictors of response to NSAIDs on the univariate level with three different definitions of responder

Total WOMAC score at baseline

-

0.43*

0.22-0.82

-

Age > 57 (years)

1.20

0.66-2.16

0.41

0.21-0.77

1.14

0.61-2.13

BMI > 31 (kg/m2)

1.79*

1.02-3.28

0.81

0.43-1.49

1.18

0.63-2.18

Joint space width > 3.5 mm

0.48*

0.23-0.98

1.59+

0.76-3.21

0.61+

0.28-1.30

Knee height > 49 cm

2.46*

1.18-5.13

0.75

0.36-1.51

1.05

0.49-2.25

KL Grade > 2

1.34

0.71-2.54

0.47*

0.23-0.97

1.26

0.68-2.45

Duration of OA > 4 (month)

1.14

0.51-2.56

0.75

0.39-1.72

1.38

0.59-3.21

Previous knee injuries

5.27*

1.83-15.38

2.25+

0.86-5.85

3.92*

1.59-9.67

Co morbidities

0.71

0.38-1-28

0.67+

0.35-1.21

0.60+

0.32-1.13

Existence of back pain

1.77

0.15-19.9

18.2

0.51-24.5

3.39

0.31-38.2

High level of education

2.19*

1.15-4.19

0.63

0.33-1.21

1.72+

0.91-3.25

Number of pregnancies > 4

2.48*

1.06-5.73

0.51+

0.21-1.21

1.92+

0.81-4.51

EQ index at baseline > 0.36

0.5+

0.24-1

1.47

0.73-3.07

0.58+

0.27-1.26

VAS EQ 5D at baseline > 40

0.21*

0.09-0.41

1.56+

0.73-3.32

0.29*

0.12-0.71