ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response

Table 2 Tail suspension and prepulse inhibition tests of Grin1^Rgsc174/Grin1⁺mice

Behavioral test		Wild-type	Mutant	F value(degree of freedom)	p value
Tail suspension test
	Immobility	15.3 (±3.8)	30.3 (±8.3)	F_1,14 = 3.152	0.098
Prepulse inhibition test
	Startle stimulus/Prepulse (dB)
	110/74	−0.8 (±11.6)	−4.1 (±12.3)	F_1,18 = 0.357	0.558
	110/78	−12.8 (±14.9)	−4.9 (±17.6)	F_1,18 = 0.357	0.558
	120/74	−14.3 (±6.5)	−14.3 (±10.5)	F_1,18 = 1.589	0.224
	120/78	−6.1 (±9.5)	−6.1 (±9.6)	F_1,18 = 1.589	0.224

ISSN: 1756-0500