Table 2 Number of dialysis sessions, average of the maximum plasma concentration (C max ) as IU mL -1 or μg mL -1 (as hexuronic acid content) and t ½ (as min) for each individual patient
From: Bovine and porcine heparins: different drugs with similar effects on human haemodialysis
Porcine | Bovine | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Patient | Dose of heparin | Number of sessions | Cmaxin plasma | t½ | Number of sessions | Cmaxin plasma | t½ | ||
IU x 103 | IU mL-1 | μg mL-1 | Min | IU mL-1 | μg mL-1 | min | |||
1 | 12 | 3 | 2.53 | 3.47 | 141.0 | 3 | 2.57 | 7.08 | 160.9 |
2 | 9 | 3 | 2.62 | 3.59 | 144.8 | 3 | 2.01 | 5.54 | 151.7 |
3 | 12 | 2 | 2.66 | 3.65 | 126.7 | 3 | 1.77 | 4.88 | 142.3 |
4 | 10 | 2 | 2.59 | 3.55 | 168.5 | 2 | 1.69 | 4.66 | 136.1 |
5 | 9 | 1 | 2.14 | 2.94 | 159.3 | 2 | 1.54 | 4.24 | 152.8 |
6 | 11 | 2 | 1.73 | 2.37 | 105.2 | 3 | 1.06 | 2.92 | 129.1 |
7 | 6 | 3 | 1.95 | 2.67 | 127.0 | 3 | 1.35 | 3.72 | 116.2 |
8 | 7 | 3 | 1.91 | 2.62 | 138.9 | 2 | 1.24 | 3.42 | 145.8 |
9 | 10 | 3 | 1.52 | 2.08 | 111.6 | 3 | 1.01 | 2.78 | 117.5 |
10 | 9 | 3 | 1.31 | 1.80 | 112.3 | 4 | 1.26 | 3.47 | 118.7 |
11 | 8 | 3 | 1.52 | 2.08 | 116.1 | 3 | 1.69 | 4.66 | 124.0 |
12 | 9 | 3 | 2.32 | 3.18 | 148.0 | 3 | 2.10 | 5.79 | 146.1 |
13 | 8 | 2 | 3.18 | 4.36 | 142.6 | 3 | 2.26 | 6.23 | 151.9 |
14 | 5 | 3 | 1.36 | 1.87 | 110.8 | 3 | 1.23 | 3.39 | 133.5 |
15 | 12 | 2 | 2.23 | 3.06 | 128.1 | 3 | 1.91 | 5.26 | 123.7 |
16 | 12 | 3 | 2.82 | 3.87 | 129.5 | 3 | 1.69 | 4.66 | 134.4 |
17 | 10 | - | - | - | - | 3 | 1.27 | 3.50 | 133.6 |
Total | 41 | 2.15±0.56 | 2.95±0.77 | 131.3±18.3 | 49 | 1.63±0.44 | 4.48±1.22 | 136.4±13.8 | |