Adverse events in the treatment of MDR-TB patients within and outside the NTP in Pham Ngoc Thach hospital, Ho Chi Minh City, Vietnam

Table 3 Frequency of adverse drug events observed during MDR treatment, Pham Ngoc Thach hospital, 2010

Type of adverse event^a	Total		Mild^b	Moderate^c	Severe^d	No information
Type of adverse event^a	n	%	Mild^b	Moderate^c	Severe^d	No information
Total	226	100.0	78	32	25	91
Arthralgia/joint pain	81	35.8	25	16	7	33
Gastrointestinal	32	14.2	18	2	0	12
Ototoxicity	19	8.4	8	3	4	4
Cutaneous reaction	15	6.6	4	4	0	7
Giddiness	13	5.8	2	1	0	10
Psychiatric symptoms	10	4.4	5	1	3	1
Hepatitis	7	3.1	1	2	4	0
Peripheral neuropathy	7	3.1	3	1	0	3
Renal toxicity	5	2.2	2	0	3	0
Visual symptoms	5	2.2	4	0	0	1
Insomnia	5	2.2	0	0	0	5
Hypothyroidism	3	1.3	0	2	1	0
Central nervous system	1	0.4	0	0	0	1
Others	23	10.2	6	0	3	14

^a An individual patient could have had more than 1 adverse event during the MDR treatment period
^b Mild: the drug was continued at the same dose, with or without ancillary drug prescribed, e.g., reassurance
^c Moderate: drug was continued at a reduced dose, with an ancillary drug prescribed
^d Severe: drug was changed or stopped and/or all medical treatment was stopped

ISSN: 1756-0500