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Table 1 Published cases of prostaglandin analogue related cystoid macular edema after uncomplicated cataract surgery in eyes without other risk factors

From: Cystoid macular edema associated with preservative-free latanoprost after uncomplicated cataract surgery: case report and review of the literature

Study

PGA

Time from cataract surgery and CME diagnosis

Duration of PGAs treatment

Outcome

Action taken

Additional information

Costagliola et al. [5]

LP

2 years

5 days

Complete resolution of CME within days

LP discontinuation and treatment with diclofenac

 

Altintas et al. [6]

LP

10 days

3 years

Complete resolution of CME in 3 months

Discontinuation of LP and initiation of topical and oral acetazolamide

Pseudoexfoliative glaucoma

LP not discontinued perioperatively

LP

1 month

2 months

CME resolved in 4 months

Initiation of ketorolac eye drops and oral acetazolamide

LP was discontinued 1 day preoperatively and was never re-administered

Extracapsular extraction

Dhingra et al. [7]

LP

3 months

Unknown

CME resolved

LP discontinuation and sub-Tenon’s triamcinolone injection

Only clinical diagnosis

LP not discontinued perioperatively

Ozdemir et al. [8]

LP

2 years

1 month

CME resolution in 3 weeks

LP discontinuation

Extracapsular cataract extraction

Serous retinal detachment

Agange et al. [9]

LP

4 months

Years

CME resolved

LP discontinuation and treatment with diclofenac

Advanced pigmentary glaucoma

CME recurred twice after PGA administration

LP was resumed immediately postoperatively

Panteleontidis et al. [10]

LP

3 months

4 years

Complete resolution of CME 1 month later Recurrence of CME after LP administration

Discontinuation of LP

Pseudoexfoliative glaucoma

No statement of LP discontinuation perioperatively

LP

3 weeks

7 years

Complete resolution of CME 3 weeks later

LP discontinuation and treatment with ketorolac

Pseudoexfoliative glaucoma

No statement of LP discontinuation perioperatively

LP

1 month

2 years

Complete resolution of CME 3 weeks later

LP discontinuation and treatment with ketorolac

Pseudoexfoliative glaucoma No statement of LP discontinuation perioperatively

Sacchi et al. [11]

Tafluprost

2 months

1 year

Refractory CME which resolved after an intravitreal implant of dexamethasone

Tafluprost discontinuation

Preservative free tafluprost

Treatment with topical nepafenac and oral indomethacin, sub-Tenon’s, dexamethasone intravitreal implant

Serous retinal detachment

LP not discontinued perioperatively

  1. PGA Prostaglandin analogue, CME Cystoid macular edema, LP Latanoprost