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Table 1 Zone diameter interpretive standards and MIC breakpoints for B. pseudomallei used in the study

From: Antimicrobial susceptibility pattern of clinical isolates of Burkholderia pseudomallei in Bangladesh

Antimicrobial agents

Disk diffusion test

MIC (µg/ml)

Disk content (µg)

Zone diameter (mm)

R

I

S

S

I

R

Ceftazidimea, b

30

≤14

15–16

≥18

≤8

16

≥32

Imipenema, b

10

≤15

16–18

≥19

≤4

8

≥16

Amox–Clava,d

20/10

≤13

14–17

≥18

≤8/4

16/8

≥32/16

Pip–Tazob, c

100/10

≤14

15–20

≥21

≤16/4

32/4–64/4

≥128/4

TMP–SMXa, d

1.25/23.75

≤10

11–15

≥16

≤2/38

≥4/76

Tetracyclinea, d

30

≤11

12–14

≥15

≤4

8

≥16

Amikacinb, c

30

≤14

15–16

≥17

≤16

32

≥64

Gentamicinb, c

10

≤12

13–14

≥15

≤4

8

≥16

  1. TMPSMX trimethoprim/sulfamethoxazole, PipTazo piperacillin–tazobactam, AmoxClav amoxicillin/clavulanic acid, MIC minimum inhibitory concentration
  2. aMIC interpretive standards defined in M45-A2, CLSI guideline for B. pseudomallei [19]
  3. bZone diameter interpretive standards of CLSI for P. aeruginosa by disk diffusion method [20]
  4. cMIC interpretive standard of CLSI for P. aeruginosa [20]
  5. dZone diameter interpretive standards of CLSI for Enterobacteriaceae by disk diffusion method [20]