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Table 1 Clinical data on diagnoses, health-related conditions, operations, investigations and biochemistry analyses 1

From: Epidemiological description and trajectories of patients with prostate cancer in Denmark: an observational study of 7448 patients

 

Unaggressive PC

Aggressive PC (not advanced)

Aggressive PC (advanced)

Diagnoses and health-related conditions2

 Total ND

147,743

10,759

16,874

 Mean ND per patient

23.3a

25.6a

24.6a

 Mean ND per patient (excluding outlier patients)3

14.8a

14.4a

16.2b

 Median ND per patient

12a

12a

14b

 Npatients (% of patients) with ≥ 1 code

5972(94.2%)a

390(92.6%)a

664(96.8%)b

 Total ND (unrepeated for each patient)

41,373

2963

4928

 Mean ND per patient (unrepeated for each patient)

6.52a

7.04ab

7.18b

 Median ND per patient (unrepeated for each patient)

5a

5a

6b

Biochemistry analyses and biomarkers

 Total Nanalyses

43,263

3485

5731

 Mean Nanalyses per patient

6.8a

8.3b

8.4b

 Mean Nanalyses per patient (excluding outlier patients)3

4.0a

4.1a

5.1b

 Median Nanalyses per patient

3a

3a

3a

 Total Nbiomarkers

545,347

45,057

71,569

 Mean Nbiomarkers per patient

86.0a

107b

104b

 Mean Nbiomarkers per patient (excluding outlier patients)3

44.8a

44.7a

63.2b

 Median Nbiomarkers per patient

25a

33ab

38b

Operations and investigations4

 Total NOI

485

34

55

 Mean NOI per patient

0.076a

0.081a

0.080a

 Median NOI per patient5

0a

0a

0a

 Npatients (% of patients) with ≥ 1 code

144(2.27%)a

12(2.85%)a

19(2.77%)a

 Total NOI (unrepeated for each patient)

191

15

23

 Mean NOI per patient (unrepeated for each patient)

0.030a

0.036a

0.034a

 Median NOI per patient (unrepeated for each patient)5

0a

0a

0a

Specific prostate investigations

 Ultrasound

Mean

0.47a

0.38b

0.34b

N (%) investigations

2954 (46.6%)a

161 (38.2%)b

234 (34.1%)b

N (%) patients with ≥ 1

2415 (38.1%)a

146 (34.7%)ab

216 (31.5%)b

 Biopsy

Mean

0.58a

0.44b

0.43b

N (%) biopsies

3676 (58.1%)a

187 (44.2%)b

294 (42.9%)b

N (%) patients with ≥ 1

3125 (49.3%)a

179 (42.5%)b

282 (41.1%)b

  1. 1 Different letters (a and b) indicate statistically significant differences between categories (unaggressive PC, aggressive PC not advanced and Aggressive PC advanced) at p-value < 0.05 using test of equal proportions (for rates), ANOVA and Tukey test (for means) and Mood’s Median Test and post hoc test (for medians)
  2. 2 ND = Number of registered codes on diagnoses and health related conditions (starting with D in SKS)
  3. 3 Data lying outside Q3 + 1.5*IQR or Q1-1.5*IQR is considered as an outlier
  4. 4 NOI = Number of registered codes on operations and investigations (starting with K and U in SKS)
  5. 5 Median equal to 0 is obtained, since > 50% of the values are 0