Table 5 Variables tested as potential confounders with MDS plot y-axis using a generalised linear model fit
From: Comparison of T-cell receptor diversity of people with myalgic encephalomyelitis versus controls
Variable | Estimate | Std. Error | t-value | \(\varvec{P}\varvec{r}(>|\varvec{t}\left|\right)\) | Significance |
|---|---|---|---|---|---|
(Intercept) | 4.93E + 10 | 8.91E + 10 | 0.553 | 0.581 | |
ME(mm) | -1.48E + 01 | 1.29E + 02 | -0.115 | 0.908 | |
ME(sa) | 1.77E + 02 | 1.48E + 02 | 1.20 | 0.235 | |
MS | 1.50E + 02 | 1.30E + 02 | 1.16 | 0.249 | |
Age | 3.49E + 01 | 1.72E + 02 | 0.202 | 0.840 | |
PBMC Number | -2.28E + 01 | 4.11E + 01 | -0.554 | 0.580 | |
CD8+ % Input | 2.70E + 00 | 1.15E + 01 | 0.234 | 0.815 | |
CD8 + Cells Post-selection | 3.02E + 02 | 3.15E + 02 | 0.959 | 0.340 | |
Purity | -4.29E + 00 | 3.35E + 00 | -1.28 | 0.203 | |
DNA Extracted (µg) | 2.42E + 00 | 6.07E + 01 | 0.04 | 0.968 | |
DNA Yield (ng) | 1.88E-01 | 1.57E-01 | 1.20 | 0.232 | |
Demultiplexed Reads (641) | 5.19E-05 | 2.20E-05 | 2.36 | 0.0199 | * |
PEAR Assembled (641) | -5.77E + 00 | 6.79E + 00 | -0.85 | 0.397 | |
Demultiplexed Reads (782) | -6.02E-06 | 1.72E-05 | -0.351 | 0.726 | |
PEAR Assembled (782) | -1.04E + 00 | 7.51E + 00 | -0.138 | 0.890 | |
α Coding Junctions | 1.56E-01 | 9.56E-02 | 1.63 | 0.105 | |
β Coding Junctions | -4.50E-01 | 1.33E-01 | -3.38 | 0.000998 | *** |
γ Coding Junctions | -2.47E-01 | 1.23E-01 | -2.00 | 0.0474 | * |
α % | -4.93E + 10 | 8.91E + 10 | -0.553 | 0.581 | |
β % | -4.93E + 10 | 8.91E + 10 | -0.553 | 0.581 | |
γ % | -4.93E + 10 | 8.91E + 10 | -0.553 | 0.581 |