Predictors for CD4 cell count and hemoglobin level with survival time to default for HIV positive adults under ART treatment at University of Gondar Comprehensive and Specialized Hospital, Ethiopia

Table 6 Bayesian joint model parameter estimates for survival sub-model

Variables	Categories	Posterior mean	Standard error	HR	95% CI for HR		p-value
Variables	Categories	Posterior mean	Standard error	HR	Lower	Upper	p-value
Hematocrit	–	0.0157	0.0015	1.0158	1.0128	1.0188	0.001
BMI	–	0.0498	0.0081	1.0511	0.0191	1.1294	0.221
Platelet	–	0.0532	0.0054	1.0546	1.0435	1.0658	0.001
Weight	–	0.0800	0.0040	1.0833	1.0748	1.0918	0.000
Lymphocyte	–	0.0641	0.0042	1.0602	1.0575	1.0750	0.041
Sex (Ref = male)	Female	0.4085	0.0044	1.5046	1.1474	1.9975	0.004
Adherence (Ref = Poor)	Fair	0.0734	0.0041	1.0762	0.4874	3.4384	0.508
Adherence (Ref = Poor)	Good	1.2329	0.0047	3.4312	2.4006	4.9392	0.000
WHO (Ref = Stage-I)	Stage-II	− 0.4223	0.0053	0.6555	0.3421	0.8891	0.002
	Stage-III	− 0.5700	0.0047	0.5655	0.0949	0.2734	0.000
	Stage-IV	− 0.2498	0.0064	0.7789	0.7692	0.7888	0.000
OIs (Ref = No)	Yes	0.1442	0.0039	1.1551	1.0908	1.4854	0.000
OCC(Ref = No)	Yes	0.0880	0.0038	1.0919	0.0839	1.1002	0.108
Disclosure (Ref = No)	Yes	− 0.3333	0.0045	0.7166	0.5458	0.9514	0.010
Tobacco (Ref = No)	Yes	− 0.5034	0.0047	0.6045	0.5989	0.6101	0.012
Alcohol (Ref = No)	Yes	− 0.3281	0.0036	0.7203	0.7152	0.7254	0.020
\({\alpha }_{1}\)	–	0.0037	0.0001	1.0037	1.0035	1.0039	0.001
\({b}_{1}\)	–	0.0021	0.0010	1.0021	1.0001	1.0041	0.004
\({\alpha }_{2}\)	–	0.4634	0.0014	1.5895	1.3975	1.8175	0.000
\({b}_{2}\)	–	0.0013	0.0001	1.0013	1.0011	1.0015	0.001

\({\alpha }_{1}\) and \({\alpha }_{2}\) represents the association parameter of random intercept for CD4 and Hemoglobin, \({b}_{1}\) and \({b}_{2}\) indicates the association parameter of random slope for CD4 and Hemoglobin, CI credible interval and ref is reference category

ISSN: 1756-0500