Table 3 Association of collagen gene cluster expression and outcomes of BA patients after Kasai procedure

Cirrhosis (ΔC_T ± SD) (n = 5)

12.71 ± 4.02

9.76 ± 4.2

17.29 ± 9.44

2.46 ± 1.45

Non-cirrhosis (ΔC_T ± SD) (n = 15)

7.51 ± 1.65

6.51 ± 2.18

9.74 ± 3.76

2.35 ± 0.84

ΔΔC_T (95% CI)

5.2 (1.65–9.74)

3.26 (0.01–6.5)

7.55 (0.92–14.17)

0.11 (− 1.52–1.74)

Fold change (2^−ΔΔC_T)

36.63

9.55

187.04

1.08

p-value

0.0085*

0.04*

0.028*

0.879

Age at Kasai surgery ≥ 90 days (n = 15)

10.34 ± 7.51

8.41 ± 2.9

12.2 ± 7.35

3.5 ± 1.78

Age at Kasai surgery < 90 days (n = 5)

10.25 ± 3.02

7.34 ± 4.82

10.85 ± 1.81

2.61 ± 1.16

ΔΔC_T (95% CI)

0.09 (-7.31 – 7.48)

1.07 (− 2.64 – 4.79)

1.35 (− 7.97–10.67)

2.9 (− 1.17–2.95)

Fold change (2^−ΔΔC_T)

1.06

2.11

2.55

1.85

p-value

0.981

0.551

0.762

0.371

Died (ΔC_T ± SD) (n = 13)

11.02 ± 4.68

8.66 ± 3.27

11.99 ± 4.84

3.4 ± 1.2

Survived (ΔC_T ± SD) (n = 7)

9.1 ± 1.99

8.35 ± 2.42

8.27 ± 4.47

2.53 ± 1.94

ΔΔC_T (95% CI)

1.92 (− 2.07–5.91)

0.31 (− 2.75–3.37)

3.72 (− 1.76–9.21)

0.87 (− 1.33–3.07)

Fold change (2^−ΔΔC_T)

3.78

1.24

13.21

1.83

p-value

0.323

0.832

0.168

0.409