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Table 1 Scoring of tumor-infiltrating lymphocytes (TILs). (Cyclo = cyclophosphamide, GZM B = granzyme B by immunohistochemistry). PD-1 score was calculated by multiplying the staining intensity score with the score of percentage of the immunoreactive cells

From: Metronomic cyclophosphamide and metformin inhibited tumor growth and repopulated tumor-infiltrating lymphocytes in an experimental carcinoma model

Specimen

TILs

GZM B

PD-1 score

Cyclo high

-

-

2

Cyclo high

-

-

Cyclo + metformin

+

Mild

6

Cyclo + metformin

+

Mild

Metformin

+

-

3

Metformin

+

Mild

Cyclo low

-

-

4

Cyclo low

-

-

Untreated

-

-

2

Untreated

+

Mild

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BMC Research Notes

ISSN: 1756-0500

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