Outcomes | Estimatea | 95% CI | p value | Adjusted Estimateb | 95% CI | p value |
---|---|---|---|---|---|---|
Dichotomous outcomes | ||||||
Severe/critical COVID-19c | 2.89 | 2.41, 3.47 | < 0.001 | |||
Full/partial improvement of neurologic deficit/s | 0.44 | 0.29, 0.67 | < 0.001 | 0.94 | 0.59, 1.51 | 0.799 |
All-cause mortality | 2.43 | 1.99, 2.95 | < 0.001 | 1.06 | 0.85, 1.33 | 0.577 |
Death from cardiac cause | 2.61 | 1.79, 3.81 | < 0.001 | 2.22 | 1.49, 3.32 | < 0.001 |
Respiratory failure | 3.06 | 2.52, 3.71 | < 0.001 | 1.21 | 0.97, 1.51 | 0.084 |
Prolonged duration of ventilator dependence | 0.48 | 0.30, 0.77 | 0.002 | 0.99 | 0.60 1.62 | 0.957 |
Prolonged length of ICU stay | 1.39 | 0.89, 2.17 | 0.150 | 1.58 | 1.00, 2.52 | 0.052 |
Prolonged length of hospital stay | 1.43 | 1.19, 1.70 | < 0.001 | 1.16 | 0.96, 1.40 | 0.124 |
Time-to-event outcomes | ||||||
All-cause mortality | 1.43 | 1.21, 1.69 | < 0.001 | 0.98 | 0.83, 1.17 | 0.846 |
Death from cardiac cause | 3.02 | 2.18, 4.18 | < 0.001 | 1.91 | 1.34, 2.71 | < 0.001 |
Respiratory failure | 2.59 | 2.20, 3.03 | < 0.001 | 1.07 | 0.90, 1.26 | 0.437 |