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Fig. 3 | BMC Research Notes

Fig. 3

From: Is bladder outlet obstruction rat model to induce overactive bladder (OAB) has similarity to human OAB? Research on the events in smooth muscle, collagen, interstitial cell and telocyte distribution

Fig. 3

Transmission electron microscopy of overactive bladder in BOO 6 W, BOO 8 W, and sham groups of female rat animal model. (A) Overactive bladder: Condensation of collagen (C) surrounding a fibroblast cell (Fb). Scale bar 2 μm. (B) Overactive bladder: Condensation of collagen (C) and absent telocyte. Scale bar 2 μm. (C) Overactive bladder: Smooth muscle cell (SMC) adjacent to bundle of collagen (C). Telocyte (TC) (marked boundaries with blue) having its nucleus (N) and long slender cytoplasm of Telopode (Tp) containing a vesicle pointed with small orange arrows and is situated between condensation of collagen. Scale bar 1 μm. (D) Overactive bladder: Smooth muscle cell (SMC) with many telopodes extensions (Tp) in between. Telocyte (TC) (marked boundaries with blue) containing a nucleus (N) and long cylindrical telopodes (Tp) that contains a vesicle (V) pointed with small orange arrows and is situated between condensation of collagen. Scale bar 1 μm. (E) Normal control. Smooth muscle cells (SMC) are orderly arranged with close cell to cell contact with minimal collagen in the interstitium. Scale bar 2 μm (F) Normal control: Telocyte (TC), nucleus (N), telopodes (Tp) contain many vesicles pointed with small orange arrows. Scale bar 1 μm

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