Table 4 Comparison of frozen section with final (paraffin) for the evaluation of margins of oral squamous cell carcinoma with respect to tumor grade and stage
Variables | Frozen section margin status | Final (paraffin) section margin status | Sensitivity | Specificity | PPV | NPV | Diagnostic Accuracy | ||
|---|---|---|---|---|---|---|---|---|---|
Positive | Negative | ||||||||
Tumor stage | Stage-I | Positive | 29 | 6 | 78.38% | 88.24% | 82.86% | 84.91% | 84.09% |
Negative | 8 | 45 | |||||||
Stage-II | Positive | 61 | 0 | 89.70% | 100% | 100% | 88.70% | 94.30% | |
Negative | 7 | 55 | |||||||
Stage-III/IV | Positive | 29 | 0 | 100% | 100% | 100% | 100% | 100% | |
Negative | 0 | 11 | |||||||
Tumor grade | Grade 1 | Positive | 0 | 6 | 0.00% | 91.40% | 0.00% | 98.50% | 90.10% |
Negative | 1 | 64 | |||||||
Grade 2 | Positive | 82 | 0 | 87.20% | 100% | 100% | 79.60% | 91.50% | |
Negative | 12 | 47 | |||||||
Grade 3 | Positive | 37 | 0 | 94.80% | 0.00% | 100% | 0.00% | 94.80% | |
Negative | 2 | 0 | |||||||