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Table 2 Genes Involved in strain-specific insertions.

From: Analysis of the genetic variation in Mycobacterium tuberculosis strains by multiple genome alignments

Position

Size

Genes Involved

  

H37Rv

3551227–3552586

1359

Intergenic region between Rv3185 (Probable transposase) and Rv3188 (Hypothetical protein)

  

H37Ra

13627–14986

1359

Insertion of the IS6110 element between Rv0010c (Probable conserved membrane protein) and Rv0011c (Hypothetical protein)

1989343–1990797

1437

Insertion of the IS6110 element on the ipl locus

  

CDC1551

804474–804691

217

Intergenic region between rplW (50S ribosomal protein L23) and rplB (50S ribosomal protein L2)

2341782–2341840

58

MT2144 (Hypothetical protein)

  

F11

934662–936021

1359

IS6110 insertion in intergenic region between hypothetical proteins TBFG_10851 and TBFG_10853

1945992–1947351

1359

IS6110 insertion in Rv1724c (Hypothetical protein)

1992354–1993713

1359

IS6110 insertion in cut1 (Probable cutinase)

1997360–1998719

1359

IS6110 insertion in intergenic region between wag22 (PE-PGRS) and Rv1760 (Hypothetical protein)

2004182–2005541

1359

IS6110 insertion in intergenic region between hypothetical proteins Rv1765c and Rv1766

2017862–2019221

1359

IS6110 insertion in cyp144 (Cytochome P450)

2270442–2271801

1359

IS6110 insertion in Rv2015c (Hypothetical protein)

2349289–2350648

1359

Intergenic region between Rv2077c (Possible conserved transmembrane protein) – Rv2078 (Hypothetical protein)

2697325–2698684

1359

IS6110 insertion in Rv2390c (Hypothetical protein)

3492136–3493495

1359

IS6110 insertion in Rv3113 (Probable phosphatase)

3564263–3565622

1359

IS6110 insertion in intergenic region between Rv3183 (Possible transcriptional regulatory protein) – TBFG_13208 (Conserved hypothetical protein)

3831596–3831772

176

Intergenic region between Rv3401 (Hypothetical protein) and Rv3402c (Hypothetical protein)

3853062–3860408

2394

TBFG_13461 (Hypothetical protein) – TBFG_13462 (Hypothetical protein) – TBFG_13463 (Hypothetical protein) – TBFG_134614 (Probable Transposase) – Intergenic region

  

Haarlem

1071617–1072976

1359

IS6110 insertion in Rv0963c (Conserved hypothetical protein)

1714841–1716200

1359

IS6110 insertion in mmpl12 (Transmembrane protein)

1834511–1834569

58

Rv1637c (Hypothetical protein)

1973210–1973436

226

PPE24

2606037–2607396

1359

IS6110 insertion in Rv2336 (Hypothetical protein)

4144939–4144997

58

leuA (2-isopropylmalate synthase)

  

C

4088473–4088705

232

Rv3680 (Probable anion transporter ATPase)

  1. Gene names are according to Tuberculist when homologous to MTB H37Rv, if not, genes are named according to the annotation of the respective genome.