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Table 1 GO terms containing differentially expressed genes between OSCC subsite-related clusters

From: Global gene expression profiling of oral cavity cancers suggests molecular heterogeneity within anatomic subsites

GO Term

p Value

Gene Symbol

GO:0006412:translation

1.55E-07

C15ORF15, CEBPG, DARS2, DDX1, DENR, EEF1A1, EIF1, EIF1AY, EIF2B1, EIF2B3, EIF2C4, EIF3S7, EIF4A1, EIF4EBP1, ETF1, GSPT1, HARSL, HBS1L, IGF2BP2, JTV1, LARS, LOC151507, MRPL1, MRPL10, MRPL20, MRPL22, MRPL35, MRPL37, MRPL45, MRPL9, MRPS15, MRPS16, MRPS7, MTIF2, NARS2, NFKB1, PAIP2, PDF, PET112L, PRG3, RPL13, RPL18A, RPL19, RPL26, RPL26L1, RPL27, RPL35A, RPL36A, RPL4, RPL6, RPL7, RPL7A, RPLP1, RPS14, RPS15A, RPS2, RPS24, RPS26, RPS26E, RPS26L, RPS27, RPS27A, RPS3, RPS3A, RPS7, SAMD4A, SARS, SECISBP2, SLA/LP, SRP9, STAT5B, TNIP1, TRIP11, TSFM, TUFM, WBSCR1, ZFP36L1

GO:0000087:M phase of mitotic cell cycle

5.53E-06

ANAPC11, APRIN, AURKB, BIRC5, C20ORF172, CCNB1, CCNK, CDC2L5, CLASP2, CSPG6, EML4, FAM33A, GTSE1, KIF2C, KNTC1, LUZP5, MAD2L1, MPHOSPH6, NUDC, PAM, PB1, PRMT5, RAD21, RAN, RUVBL1, SMC4L1, SPAG5, SPBC25, STAG1, SUGT1, TARDBP, TTN, TXNL4B, ZWINT

GO:0007067:mitosis

1.21E-05

ANAPC11, APRIN, AURKB, BIRC5, C20ORF172, CCNB1, CCNK, CDC2L5, CLASP2, CSPG6, EML4, FAM33A, GTSE1, KIF2C, KNTC1, LUZP5, MAD2L1, NUDC, PAM, PB1, PRMT5, RAD21, RAN, RUVBL1, SMC4L1, SPAG5, SPBC25, STAG1, SUGT1, TARDBP, TTN, TXNL4B, ZWINT

GO:0006325:establishment and/or maintenance of chromatin architecture

1.37E-05

ARID1B, BAZ1B, C11ORF30, CBX3, CDYL, CEBPG, CHAF1A, CHD2, CHD9, EHMT2, EPC1, FBXL11, GCN5L2, H2AFX, H2AFZ, HDAC4, HDAC6, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST3H3, HMGB2, HP1BP3, JARID1B, JMJD1C, JMJD2C, MBD3, MCM2, MLL3, NAP1L1, NCOR1, NSD1, PB1, PRMT5, RBBP4, RBL1, RERE, RUVBL1, SAS10, SET, SMARCB1, SMARCC1, WHSC1

GO:0000279:M phase

2.05E-05

ANAPC11, APRIN, AURKB, BIRC5, C20ORF172, C8ORF1, CCNB1, CCNK, CDC2L5, CLASP2, CSPG6, CTA-250D10.11, EML4, FAM33A, GTSE1, H2AFX, KIF2C, KNTC1, LUZP5, MAD2L1, MPHOSPH6, NUDC, PAM, PB1, PRMT5, RAD21, RAN, REC8L1, RUVBL1, SMC4L1, SPAG5, SPBC25, STAG1, SUGT1, TARDBP, TTN, TXNL4B, ZWINT

GO:0006323:DNA packaging

2.14E-05

ARID1B, BAZ1B, C11ORF30, CBX3, CDYL, CEBPG, CHAF1A, CHD2, CHD9, EHMT2, EPC1, FBXL11, GCN5L2, H2AFX, H2AFZ, HDAC4, HDAC6, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST3H3, HMGB2, HP1BP3, JARID1B, JMJD1C, JMJD2C, MBD3, MCM2, MLL3, NAP1L1, NCOR1, NSD1, PB1, PRMT5, RBBP4, RBL1, RERE, RUVBL1, SAS10, SET, SMARCB1, SMARCC1, WHSC1

GO:0009260:ribonucleotide biosynthetic process

2.12E-04

ADK, ADSL, ATP5B, ATP5C1, ATP5F1, ATP5G3, ATP5H, ATP5L, ATP5O, ATP6V1C1, CTPS, IMPDH1, NME2, PAICS, PAPSS1, PAX8, UMPS

GO:0006281:DNA repair

2.87E-04

APEX1, ATRX, BLM, C11ORF30, C2ORF13, C8ORF36, CEBPG, CHAF1A, CIB1, CSNK1D, CSPG6, ERCC8, FANCC, FEN1, FLJ40869, H2AFX, HMGB2, LIG1, MBD4, MDC1, MGMT, MLH1, MSH3, NUDT1, POLE2, RAD18, RAD21, RBX1, REV1L, RPA3, SMC5L1, SOD2, XRCC5

GO:0006396:RNA processing

8.86E-04

AQR, BCAS2, C14ORF172, C1ORF19, CROP, CSTF2T, DDX1, DDX46, DDX5, DHX35, DICER1, ERN2, EXOSC1, EXOSC3, GEMIN5, HNRPA2B1, HNRPD, HSA9761, LOC113179, LSM3, MAGOH, NHP2L1, NOL5A, PABPN1, PDCD11, POP4, PPIL3, PRPF3, PRPF38B, RPS14, SARS, SAS10, SF3B14, SF3B5, SLBP, SMN1, SMN2, SNRPA1, SNRPF, SR140, SRRM2, TARDBP, TXNL4B, U2AF1, UTP11L, UTP15, ZCRB1, ZNF265

GO:0016071:mRNA metabolic process

9.55E-04

AQR, C1ORF19, CSTF2T, DCP1A, DDX1, DDX46, DDX5, DHX35, ERN2, GEMIN5, GSPT1, HNRPA2B1, HNRPD, LSM3, LSMD1, MAGOH, NHP2L1, PABPN1, PPIL3, PRPF3, PRPF38B, SF3B14, SF3B5, SLBP, SMG7, SMN1, SMN2, SNRPA1, SNRPF, SRRM2, TARDBP, TXNL4B, U2AF1, ZCRB1, ZFP36L1, ZNF265

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BMC Research Notes

ISSN: 1756-0500

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