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Table 1 Rate of incorrect domain assignment by type of other domain

From: Protein subfamily assignment using the Conserved Domain Database

(A) Type of incorrect hit (B) # Sequences with self hit and other hit (# domains) (C) # Sequences with higher score from other hit (# domains) (D) Error rate
Self only 23918 (264) - -
Parent/ancestor 49934 (2402) 137 (58) 0.35%
Child/descendant 9822 (274) 2135 (129) 21.8%
Other domain in hierarchy 47362 (2306) 100 (37) 0.15%
Domain outside hierarchy; sequence not in other domain model 6747 (506) 421 (32) 3.0%
Domain outside hierarchy; sequence in other domain model 736 (66) 313 (18) 21.1%
  1. (A) Classes of incorrect hits, labelled by hierarchical relationship to the specific domain. (B) Number of sequences with self hit and other hit of the respective category; the number of domains containing these sequences is in parentheses. (C) Number of sequences with other domain scoring higher than correct domain; the number of domains containing these sequences is in parentheses. (D) Error rate as percent of sequences with higher score from incorrect domain than the self hit, averaged over domains containing sequences with both types of hits.