TY - JOUR AU - Song, Ying AU - Vera, Nicole AU - Kohn, Michael H. PY - 2008 DA - 2008/12/01 TI - Vitamin K epoxide reductase complex subunit 1 (Vkorc1) haplotype diversity in mouse priority strains JO - BMC Research Notes SP - 125 VL - 1 IS - 1 AB - Polymorphisms in the vitamin K-epoxide reductase complex subunit 1 gene, Vkorc1, could affect blood coagulation and other vitamin K-dependent proteins, such as osteocalcin (bone Gla protein, BGP). Here we sequenced the Vkorc1 gene in 40 mouse priority strains. We analyzed Vkorc1 haplotypes with respect to prothrombin time (PT) and bone mineral density and composition (BMD and BMC); phenotypes expected to be vitamin K-dependent and represented by data in the Mouse Phenome Database (MPD). SN - 1756-0500 UR - https://doi.org/10.1186/1756-0500-1-125 DO - 10.1186/1756-0500-1-125 ID - Song2008 ER -