Figure 3

Porcine PPARGC1A protein and comparison with the putative aa sequence of both exon 8 splice variants. (a) The functional domains of the complete porcine PPARGC1A protein are shown, together with the part of its amino acid sequence (Cprot) that is altered in the splice variants. NRF-1, nuclear respiratory factor 1; PPARγ, peroxisome proliferator-activated receptor γ; MEF2C, myocyte enhancer factor 2C; SR, serine-arginine-rich domain; RRM, RNA recognition motif [1, 22–24].(b) The putative protein and aa sequence of the exon 8 splice variant in which the last 66 bp of exon 8 are conserved (SV2). (c) The putative protein and aa sequence of the exon 8 splice variant in which exon 8 is completely spliced out (SV3). * indicates the stop codon of both splice variants.