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Table 5 Power of MDR with and without omnibus permutation testing and false positive rate with permutation testing.

From: The effect of alternative permutation testing strategies on the performance of multifactor dimensionality reduction

Epistasis Model    
Number of Functional Loci Minor Allele Frequency Heritability Power (%) Without Permutation Testing Power (%) With Permutation Testing False Positive Rate (%) With Permutation Testing
2 0.2 3%    
2 0.2 2% 90 88 0
2 0.2 1.5% 94 91 1
2 0.2 1% 70 56 6
2 0.2 0.5% 18 14 4
2 0.4 3% 93 93 2
2 0.4 2% 93 92 5
2 0.4 1.5% 95 91 1
2 0.4 1% 85 71 6
2 0.4 0.5% 25 11 0
3 0.2 3% 69 69 2
3 0.2 2% 85 85 2
3 0.2 1.5% 20 18 5
3 0.2 1% 6 2 6
3 0.2 0.5% 6 2 4
3 0.4 3% 89 89 1
3 0.4 2% 55 54 3
3 0.4 1.5% 40 34 2
3 0.4 1% 6 4 2
3 0.4 0.5% 3 0 1
4 0.2 3% 68 68 4
4 0.2 2% 59 57 8
4 0.2 1.5% 11 10 4
4 0.2 1% 10 9 2
4 0.2 0.5% 1 0 1
4 0.4 3% 60 52 1
4 0.4 2% 36 25 5
4 0.4 1.5% 4 4 7
4 0.4 1% 3 2 6
4 0.4 0.5% 0 0 3
5 0.2 3% 35 35 3
5 0.2 2% 3 3 3
5 0.2 1.5% 1 0 2
5 0.2 1% 20 11 4
5 0.2 0.5% 0 0 1
5 0.4 3% 15 10 0
5 0.4 2% 3 2 6
5 0.4 1.5% 0 0 9
5 0.4 1% 0 0 0
5 0.4 0.5% 0 0 5