Table 1 Exclusion criteria

nicotine incompatibility

history of haemolysis

history of myocardial infarction, coronary artery disease, cardiac arrhythmia or angina pectoris

Hyperthyroidism

pheochromocytoma

insulin dependent diabetes mellitus

arterial hypertension

kidney- or liver disease

patient's age under 18 or over 60 years

pregnancy and lactation

simultaneous participation in other clinical studies