Fibrosis stage ≥ 3 n = 27 | Fibrosis stage < 3 n = 33 | p value | |
---|---|---|---|
Age at biopsy (yrs) | 40.6 ± 8.7 | 38.3 ± 7.8 | ns |
Age exposed to HCV (yrs) | 20.3 ± 11.0 | 24.4 ± 7.2 | ns |
Age at HIV diagnosis (yrs) | 33.6 ± 9.6 | 33.1 ± 6.7 | ns |
HIV diagnosed in or after 1996 | 11 (41%) | 23 (70%) | 0.023 |
White | 8 (30%) | 15 (45%) | ns |
Alcohol | 6 (22%) | 12 (36%) | ns |
Diabetes Mellitus | 1 (4%) | 2 (6%) | ns |
Weight | 70.7 ± 10.0 | 73.5 ± 10.2 | ns |
Weight ≥ 75 Kg | 11 (41%) | 13 (39%) | |
Cholestrol | 4.5 ± 1.3 | 4.0 ± 1.0 | ns |
Triglycerides (TG) | 2.1 ± 1.8 | 1.8 ± 1.5 | ns |
Cholestrol/TG ratio | 5.0 ± 2.2 | 3.8 ± 1.3 | 0.02 |
Platelet count (/mm3) | 163 ± 65.5 | 228 ± 66.8 | 0.001 |
Therapy received | |||
None | 5 (18%) | 12 (36%) | Ns |
NRTI | 4 (15%) | 6 (18%) | Ns |
Duration | 11.2 ± 8.4 | 29.3 ± 17.1 | 0.16 |
Only HAART | 11 (41%) | 11 (33%) | Ns |
Duration | 29.5 ± 26.5 | 30.4 ± 27.9 | Ns |
Sequential | 7 (26%) | 4 (12%) | Ns |
Duration | 105 ± 23.3 | 77.5 ± 47.3 | 0.39 |
Steatosis | 18 (67%) | 17 (51%) | Ns |
Steatosis grade | 1.0 ± 0.9 | 0.5 ± 0.5 | 0.028 |
Necroinflammatory grade | 4.4 ± 1.9 | 3.1 ± 1.3 | 0.007 |
CD4 count (/mm3) | 370 (130–1100) | 510 (100–1200) | 0.06 |
HIV VL (copies/ml) | UD (UD-210955) | 28.5 (UD-59540) | Ns |