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Figure 1 | BMC Research Notes

Figure 1

From: Fisher: a program for the detection of H/ACA snoRNAs using MFE secondary structure prediction and comparative genomics – assessment and update

Figure 1

Idealised secondary structural representation of an H/ACA family snoRNA. H/ACA snoRNAs generally form a double hairpin structure. Each hairpin carries an internal bulge, called a pseudouridylation pocket, which may possess regions of base complementarity to a target RNA (not all snoRNAs carry two functional pseudouridylation pockets). We have designated these regions ψ1–4 for descriptive purposes. Other key motifs are the H-box, located in the hinge region between the two hairpins, and the ACA box at the 3' end of the molecule.

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