Figure 1

Experiment 1: The two colour fluorescent dye signals are converted into intensity ratio profiles. The upper and lower ratio threshold is 1.2 and 0.8 respectively. A) Ideogram showing all chromosomes. Differences seen between the female and male control (pooled gDNA from Promega) are illustrated. Gains of the X chromosome are clearly present as well as 21 duplicated and 6 deleted clones. Bars to the right (blue) indicate gains and to the left (red) losses. B) Chromosome 4 ratio plot. No deleted or duplicated clones on chromosome 4. C) Chromosome X ratio plot, a complete gain of the X chromosome can be seen.