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Table 3 Power of MDR (from Ritchie et al. 2007) to detect primary genetic model in data with genetic heterogeneity.

From: Power of grammatical evolution neural networks to detect gene-gene interactions in the presence of error

Source of Noise

Power (%) to Detect Primary Model (5,10)

 

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

GH

30

18

19

25

8

8

GE+GH

39

18

19

25

8

8

GH+PC

11

18

5

3

4

2

GH+MS

28

23

19

19

9

13

GE+GH+PC

10

18

8

4

3

3

GE+GH+MS

29

22

21

20

7

4

GH+PC+MS

12

22

5

5

2

4

GE+GH+PC+MS

16

17

4

3

1

3

  1. GE = 5% Genotyping Error; GH = 50% Genetic Heterogeneity; PC = 50% Phenocopy; MS = 5% Missing Data