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Table 5 Power of MDR (from Ritchie et al. 2007) to detect either genetic model in data with genetic heterogeneity.

From: Power of grammatical evolution neural networks to detect gene-gene interactions in the presence of error

Source of Noise

Power (%) to Detect Either Model (5,10 or 3,4)

 

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

GH

70

34

42

41

20

19

GE+GH

69

34

42

41

20

19

GH+PC

24

35

9

8

7

5

GH+MS

65

40

42

31

18

22

GE+GH+PC

27

35

10

8

7

6

GE+GH+MS

64

44

42

41

16

11

GH+PC+MS

23

38

9

10

4

6

GE+GH+PC+MS

31

36

9

7

4

3

  1. GE = 5% Genotyping Error; GH = 50% Genetic Heterogeneity; PC = 50% Phenocopy; MS = 5% Missing Data