Comparative 16S-23S rRNA region (Region-2) organization. Genes denoted by the same color (except 23S rRNA gene which is colored in light yellow) are from the same orthologous group (top COG hit). Light yellow = no COG assignment for other genes. The 16S gene is denoted in red. Explanation of terms: hem H- gene coding for phosphoribosylaminoimidazole-succinocarboxamide synthase protein; COG0739-putative membrane proteins related to metalloendopeptidases. The genomic regions matching that found in the Las cloned sequence was from genomic position 3213601 for S. meliloti; 1296782 for B. quintana; 198643 for B. melitensis; 3974043 for R. etli; 2758250 for M. loti; 1014685 in X. autotrophicus; 1457337 for R. palustris, and from 2517682 of the A. tumefaciens genomes. In addition, there are two additional coding sequences on the reverse strand in A. tumefaciens, one of which belongs to the cupredoxin family.