Figure 1

Multiple sequence alignment of the eukaryotic aTRACP gene products. Alternative transcripts identified in mouse and human are appended. The five motifs containing the seven metal coordinating residues observed in TRAcPs have been superimposed on the alignment (Me_motif_1XZW). The position is based on the WURST generated pairwise alignment between the human gene product and the sweet potato enzyme. For comparison the sequence of human TRAcP (Hsa _TRAcP) is also included, together with its secondary structure elements (h: helix; s: β-sheet; sheet 14 is omitted). Species identifiers: Hsa, Homo sapiens; Ptr, Pan troglodytes; Mmu, Mus musculus; Rno, Rattus norvegicus; Cfa, Canis familiaris; Bta, Bos Taurus; Gga, Gallus gallus; Pfa, Plasmodium falciparum.