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Figure 1 | BMC Research Notes

Figure 1

From: Mutation screening of CHD5 in melanoma-prone families linked to 1p36 revealed no deleterious coding or splice site changes

Figure 1

CHD5 sequence and amino acid alignment. a. CHD5 exon 22 sequence variant c.3351C>G [I1117M] in affected individual AH-3005 compared to wildtype sequence in unaffected individual AH-3006. b. CHD5 amino acid consensus alignment at position 1117. Comparison of human CHD5 protein with mammalian orthologs and nonmammalian paralogs. NP_001074845, Chd5 Mus musculus; NP_001038323, Chd4 Danio rerio; NP_001080504, Chd4 Xenopus laevis, NP_056372, CHD5 Homo sapiens; NP_510140, Chd-3 Caenorhabditis elegans; XP_001078944, Chd5 Rattus norvegicus; XP_525165, Chd5 Pan troglodytes; XP_546747, Chd5 Canis lupus familiaris; XP_609360, Chd5 Bos Taurus.

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