Mutation screening of CHD5 in melanoma-prone families linked to 1p36 revealed no deleterious coding or splice site changes

Table 1 CHD5 mutation screening panel from eight CMM/DN kindreds linked to 1p36

Family	Individual	Affection	CMM+DN	Mutation status
R	3002	Unaffected	No	None
R	3003	Affected	Yes	CDK4+
K	1001	Affected	Yes	CDKN2A+
K	1003	Unaffected	No	None
D	1001	Affected	Yes	CDKN2A+
D	1003	Unaffected	No	None
G	2005	Affected	Yes	CDKN2A+
G	2006	Affected	Yes	None
J	1002	Affected	Yes	CDKN2A+
J	3005	Unaffected	No	None
AH	3005	Affected	Yes	ARF+
AH	3006	Unaffected	No	None
S	1001	Affected	Yes	CDK4+
S	1003	Unaffected	No	None
A2	1001	Affected	Yes	None
A2	1019	Unaffected	No	None

ARF, CDKN2A alternative-spliced exon 1β transcript, CDKN2A, cyclin-dependent kinase inhibitor 2A, CDK4, cyclin-dependent kinase 4, CMM, cutaneous malignant melanoma; DN, dysplastic nevi.

ISSN: 1756-0500