TY - JOUR AU - Nishida, Yuichiro AU - Adati, Naoki AU - Ozawa, Ritsuko AU - Maeda, Aasami AU - Sakaki, Yoshiyuki AU - Takeda, Tadayuki PY - 2008 DA - 2008/10/28 TI - Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y JO - BMC Research Notes SP - 95 VL - 1 IS - 1 AB - SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA), but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K) is unclear. To investigate this mechanism, we compared the gene expression profiles in SK-N-SH cells and two subtypes of SH-SY5Y cells (SH-SY5Y-A and SH-SY5Y-E), each of which show a different phenotype during RA-mediated differentiation. SN - 1756-0500 UR - https://doi.org/10.1186/1756-0500-1-95 DO - 10.1186/1756-0500-1-95 ID - Nishida2008 ER -