Figure 1
From: On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y
Positions of siRNAs used to silence HCR-NTPase in SH-SY5Y. ClustalW-alignment of the eight most diverse sequences out of a group of 29 species that have been found to contain Walker A and B motifs similar to those of HCR-NTPase [3]. The sequences were from Homo sapiens, Mus musculus, Drosophila melanogaster, Aquifex aeolicus (aaTHEP1), Thermophilum pendens, Methanopyrus kandleri, an uncultured archaeon, Sulfolobus tokodaii, and Aeropyrum pernix, respectively.