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Figure 4 | BMC Research Notes

Figure 4

From: Inhibitory effects of rat bone marrow-derived dendritic cells on naïve and alloantigen-specific CD4+ T cells: a comparison between dendritic cells generated with GM-CSF plus IL-4 and dendritic cells generated with GM-CSF plus IL-10

Figure 4

IL-4 DC-T and IL-10 DC-T do not proliferate and demonstrate anergy. IL-4 DC-T and IL-10 DC-T, purified and transferred to second cultures, did not proliferate in response to subsequent stimulation with P1-loaded splenic DC (S-DC), but required the addition of IL-2 (B). In contrast, antigen-specific T cells not precultured with IL-4 DC or IL-10 DC had proliferation rates of 35,200 ± 5,100 cpm (not shown). The results (mean ± standard deviation) are representative for 3 different experiments.

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