Figure 6From: Inhibitory effects of rat bone marrow-derived dendritic cells on naïve and alloantigen-specific CD4+ T cells: a comparison between dendritic cells generated with GM-CSF plus IL-4 and dendritic cells generated with GM-CSF plus IL-10The in vivo effect of P1-loaded IL-4 DC and IL-10 DC. P1-loaded IL-4 DC and IL-10 DC prolonged the survival of allogeneic hearts grafts from Wistar-Furth in Lewis recipients. In contrast, unpulsed IL-4 DC and IL-10 DC did not influence allograft survival. The allogeneic control group I demonstrates the natural rejection of Wistar-Furth allografts by Lewis recipients (see also Table 2).Back to article page