Table 2 The effects of allopeptide pulsed and unpulsed IL-4 DC and IL-10 DC in vivo.
Group | Origin of DC | Donor of heart allografts | Survival time (d) of heart allografts in LEW recipients | MST ± SD (d)1) | Median (d) | n |
|---|---|---|---|---|---|---|
1 Syngeneic Ctr | ---2) | LEW | > 50(×3) | > 50 | 50 | 3 |
2 Syngeneic Ctr + P1 | --- | LEW | > 50(×3) | > 50 | 50 | 3 |
3 Allogeneic Ctr I | --- | WF | 7(×4), 8(×2) | 7.3 ± 0.5 | 7.0 | 6 |
4 Allogeneic Ctr I + P13) | --- | WF | 5(×4), 6(×2) | 5.3 ± 0.5 | 5.0 | 6 |
5 1 × 107 IL-4 DC | LEW 4) | WF | 6, 7(×4) | 6.8 ± 0,5 | 7.0 | 5 |
6 1 × 107 IL-4 DC + P1 | LEW | WF | 9(×3), 11 | 9.5 ± 1.0 | 9.0 | 4 |
7 1 × 107 IL-10 DC | LEW | WF | 7(×7), 8 | 7.1 ± 0.4 | 7.0 | 8 |
8 1 × 107 IL-10 DC + P1 | LEW | WF | 8, 9(×2), 10(×5) | 9.5 ± 0.8 | 10 | 8 |
9 Allogeneic Ctr II | --- | BN | 7(×3) | 7.0 | 7.0 | 3 |
10 Allogeneic Ctr II + P1 | --- | BN | 7(×3),8 | 7.3 ± 0.5 | 7.0 | 4 |
11 1 × 107 IL-4 DC | LEW | BN | 7(×3) | 7.0 | 7.0 | 3 |
12 1 × 107 IL-4 DC + P1 | LEW | BN | 7(×2), 8 | 7.3 ± 0.6 | 7.0 | 3 |
13 1 × 107 IL-10 DC | LEW | BN | 7(×3) | 7.0 | 7.0 | 3 |
14 1 × 107 IL-10 DC + P1 | LEW | BN | 7(×3) | 7.0 | 7.0 | 3 |