High-resolution analysis of aberrant regions in autosomal chromosomes in human leukemia THP-1 cell line

BMC Research Notes

Table 1 Regions of homozygous deletion in THP-1 cells.

No.	Chr	Cytoband	Position	Size (bp)	Log₂Ratio	p-value	Genes
23	chr3	q26.1	163997028 – 164101976	104949	-3.817441	3.54E-167
26	chr4	q13.2	69138837 – 69166014	27178	-5.754471	1.76E-28
28	chr4	q34.3–q35.1	182336611 – 182614113	277503	-6.675501	1.35E-175
68	chr9	p21.3	21271776 – 22236965	965190	-5.223190	0	IFNA5, KLHL9, IFNA6, IFNA13, IFNA2, IFNA8, IFNA1, IFNE1, MTAP, CDKN2A, CDKN2B, hsa-mir-31
78	chr10	q23.31	89654755 – 89680176	25422	-6.492464	3.11E-67	PTEN
124	chrX	p11.4–p11.3	41631875 – 44807102	3175228	-5.087696	0	CASK, MAOA, MAOB, NDP, EFHC2, FUNDC1, DUSP21, UTX
140	chrX	q28	153194224 – 153211806	17583	-6.345479	5.77E-25	TKTL1

Numbers in the extreme left column correspond with Aberration No. in Additional file 1. Positions were based on the UCSC March 2006 human reference sequence (hg18) (NCBI build 36.1 reference sequence).

ISSN: 1756-0500